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Althougha study explained the possible action of butaphosphan on the metabolism of dairy cows, the direct effect of butaphosphan on phosphorus and calcium homeostasis in dairy cows is still unknown.But, it has been shown that serum, liver, or kidney levels of IGF are not increased during phosphate depletion in normal rats and the reduction in auto phosphorylation reaction of IGF receptor blocks theaction of IGF at the level of cytoplasmic and nuclear in target cell.Therefore, the cross interaction of IGF and phosphate could positively affect to support the calcium homeostasis, improve the uterine muscle function and resume the ovarian function.Unfortunately, we had no data to support this suggestion in dairy cows and the future experimentations are necessary to clarify a possible the interrelationship between IGF and phosphate on phosphorus and calcium homeostasis and on energy metabolism.Although the decreased BCS after calving in dairy cows did not affect the number of insemination, it delayed intervals from calving to first insemination. The decreased BCS during first wk was associated with prolonged intervals from calving to first insemination and days open through effecting the frequency of LH pulsation and intrafollicular metabolism. Improved <a href="http://www.targetmol.com/compound/Rasagiline-Mesylate">sell Rasagiline Mesylate</a> reproductive parameters in treated groups, thus, could be related to less BCS as compared to control group.Cows with SCK have poor reproductive per formance. In cows administered with butaphosphancyanocoba lam in, days open was dshor ter than cows administered with saline.The overall pregnancy rate at DIM was about higher in treatment groups than control group.The faster uterine involution could reduce veter inary cost and increase health status through decreasing time to first insemination and pregnancy rate.cyanocobalamin combination at the level of mL kg BW everyday for days starting from DIM decreased severity of hyperketonemia, which were accompanied by less BCS lost and more milk production.This administration also stimulated uterine involution and shor tened time to first inseminationdays open as well as increased pregnancy rate.Further studies coping with more metabolic parameters would help explain the action mode of butaphosphancyanocobalamin combination.Vet Q. . Reist M, Koller A, Busato U, Kpfer J, Blum W: First ovulation and ketone body status in the early postpartum period of dairy cows.Ruegg PL, Milton URL: Body condition scores of holstein cows on prince edward island, canada: Relationships with yield, reproductive performances and disease.Walsh RB, Kelton DF, Duffield TF, Leslie KE, Walton JS, Leblanc SJ: Preva lence andrisk fac tors for postpar tum anovu latorycond it ion in da irycows.DOI. jds.S View publication stats View publication   stats The user has requested enhancement of the downloaded file.The animals were randomly distributed into four treatments, the first treatment without vitamins, second treatment was daily treated by mgewe of folic acid and third treatment was dosage of cyanocobalamin with gm per ewe at twice time every week and fourth treatment were combination treated of folic acid and B vitamin as the same concentrations above.The second phase of the experiment, which began from birth of lambs and lasted weaning age. The lambs were dosage with two vitamins by mouth method after four hours of their born as the same mentioned of ewes in the first phase of experiment.

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